Emmanuel Nzekwesi had 18 points, eight rebounds and three blocks for Oral Roberts (1-1). Sam Kearns added 11 points.
Jalon Gates had 25 points for the Huskies (0-2). Qon Murphy added 14 points. Ty Dalton had 14 points.
Ian DuBose, coming off a 20-point night in the Huskies' opener, scored only 9 points on 2-of-17 shooting.
Oral Roberts plays Tulsa on the road on Tuesday. Houston Baptist matches up against Texas Tech on Wednesday.
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